⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25343262 | 0.77 | PARP1 (0.42) | — | |
| SCHEMBL25343516 | 0.73 | BRD4 (0.38) | — | |
| SCHEMBL25438335 | 0.73 | BRD4 (0.36) | — | |
| SCHEMBL25343026 | 0.70 | HTR2A (0.31) | — | |
| SCHEMBL31402353 | 0.67 | CES1 (0.37) | — | |
| SCHEMBL25343286 | 0.63 | PDE3B (0.35) | — | |
| SCHEMBL25342592 | 0.63 | HTR2A (0.30) | — | |
| SCHEMBL23571553 | 0.60 | BRD4 (0.55) | — | |
| SCHEMBL25342482 | 0.60 | CYP2A6 (0.30) | — | |
| SCHEMBL25343264 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136577-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2025-05-01 | — | — | US | disclosed |
| EP-4472734-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2024-12-11 | — | — | EP | disclosed |
| CN-119095837-A | Heterocyclic derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |