⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19125529 | 0.78 | — | — | |
| SCHEMBL5014585 | 0.78 | — | — | |
| SCHEMBL137875 | 0.78 | — | — | |
| SCHEMBL11298975 | 0.78 | — | — | |
| SCHEMBL432317 | 0.78 | — | — | |
| SCHEMBL431549 | 0.78 | — | — | |
| SCHEMBL5532516 | 0.73 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL14790898 | 0.71 | SMN1; SMN2 (0.35) | — | |
| Vinyl Chloride SCHEMBL6417233 | 0.70 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL24300743 | 0.69 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752762-A | Substituted pyridoindoles for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2021-05-04 | — | — | CN | claimed |
| US-10702501-B2 | C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment of Mycobacterium tuberculosis and non-tubercular mycobacteria | SOUTHERN METHODIST UNIVERSITY (US) | 2020-07-07 | — | — | US | claimed |
| US-20100249396-A1 | BENZAZEPINONE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2010-09-30 | — | — | US | claimed |
| US-20090192129-A1 | BICYCLIC PYRROLE DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-07-30 | — | — | US | claimed |
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-25 | — | — | US | claimed |
| US-7452875-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-11-18 | — | — | US | claimed |
| US-7427611-B2 | Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-09-23 | — | — | US | claimed |
| US-7410962-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-08-12 | — | — | US | claimed |
| US-20080085889-A1 | Amidomethyl-Substituted 1-(Carboxyalkyl) Cyclopentyl-Carbonylamino-Benzazepine-N-Acetic Acid Compounds, Process and Intermediate Products for Their Preparation and Pharmaceutical Compositions Containing Them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-04-10 | — | — | US | claimed |
| US-20070265244-A1 | AMIDOMETHYL-SUBSTITUTED 1-(CARBOXYALKYL) CYCLOPENTYL-CARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID COMPOUNDS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-15 | — | — | US | claimed |
| CN-87100354-A | Derivatives of 7- (azabicycloalkyl) -quinolone-and 7- (azabicycloalkyl) -naphthyridonecarboxylic acids | — | 1987-09-02 | — | — | CN | claimed |
| EP-0227826-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1987-07-08 | — | — | EP | claimed |
| EP-0227100-A2 | N-Vinylimidazoles and -triazoles and pharmaceutical compositions containing them | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-07-01 | — | — | EP | claimed |
| EP-0222322-A2 | Cephalosporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-20 | — | — | EP | claimed |
| EP-0220865-A2 | Lactam derivatives, their preparation and their use as hypotensive agents | SANKYO COMPANY LIMITED (JP) | 1987-05-06 | — | — | EP | claimed |
| WO-1987000834-A1 | NOVEL VITAMIN D ANALOGUES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1987-02-12 | — | — | WO | claimed |
| US-4605651-A | BACTERICIDES | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-08-12 | — | — | US | claimed |
| EP-0124618-A1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND AGENTS FOR PROPHYLAXIS OR TREATMENT OF BACTERIA-INDUCED DISEASES | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1984-11-14 | — | — | EP | claimed |
| EP-0115308-A2 | 2-Unsaturated alkylthio-pen-2-em-3-carboxylic acids and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems | MERCK & CO. INC. (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0108942-A2 | Cephalosporin derivatives, methods of production thereof and prophylactic and therapeutic agents for bacterial infection | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1984-05-23 | — | — | EP | claimed |