Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830136 | 0.97 | KMT2A (0.50) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL747331 | 0.94 | HTT (0.44) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL27901226 | 0.92 | HTT (0.43) | HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11658709 | 0.81 | KMT2A (0.52) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL23291774 | 0.76 | POLB (0.63) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL25348596 | 0.75 | KMT2A (0.54) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8317758 | 0.75 | KMT2A (0.81) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL5674900 | 0.74 | POLB (0.52) | HTTPOLB | |
| SCHEMBL21494386 | 0.73 | KMT2A (0.61) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28151813 | 0.73 | POLB (0.68) | HTTKMT2ASMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |