Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 16/20 | 0.68 |
| ▸ | CBLC | Q9ULV8 | 2/20 | 0.68 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CBL | P22681 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31115359 | 1.00 | CBLB (0.68) | CBLBCBLCPCSK9AURKAAURKB | |
| SCHEMBL25347645 | 0.94 | CBLB (0.69) | CBLBCBLCCBL | |
| SCHEMBL31115322 | 0.94 | CBLB (0.69) | CBLBCBLCCBL | |
| SCHEMBL25348439 | 0.94 | CBLB (0.68) | CBLBCBLCPCSK9CBL | |
| SCHEMBL30521621 | 0.91 | CBLB (0.64) | CBLBCBLCCBLPDCD1CD274 | |
| SCHEMBL25349020 | 0.89 | CBLB (0.86) | CBLBCBLCPCSK9CBLPDCD1 | |
| SCHEMBL31578236 | 0.89 | CBLB (0.86) | CBLBCBLCPCSK9CBLPDCD1 | |
| SCHEMBL31578390 | 0.87 | CBLB (0.72) | CBLBCBLCPCSK9CBLPDCD1 | |
| SCHEMBL25349525 | 0.86 | CBLB (0.59) | CBLBCBLCCBL | |
| SCHEMBL31115347 | 0.86 | CBLB (0.59) | CBLBCBLCCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |