Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.72 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.72 |
| ▸ | JAK2 | O60674 | 1/20 | 0.72 |
| ▸ | GMNN | O75496 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | LYN | P07948 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350576 | 0.91 | KMT2A (0.81) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL22032660 | 0.87 | KMT2A (0.88) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL29617487 | 0.87 | KMT2A (0.88) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL25349278 | 0.86 | KMT2A (0.70) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL25349572 | 0.86 | KMT2A (0.70) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL28898446 | 0.85 | KMT2A (0.72) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL25349567 | 0.85 | KMT2A (0.68) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL18341240 | 0.84 | KMT2A (0.67) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| Niclosamide SCHEMBL6662409 | 0.84 | KMT2A (1.00) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL25346525 | 0.84 | KMT2A (0.81) | KMT2AMEN1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149548-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |