Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25347799 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2NPC1LMNATP53PKM | |
| SCHEMBL30714133 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2NPC1LMNATP53PKM | |
| SCHEMBL31059664 | 0.82 | — | — | |
| SCHEMBL25348163 | 0.82 | — | — | |
| SCHEMBL26039790 | 0.82 | — | — | |
| SCHEMBL29987604 | 0.82 | CCNE1 (0.39) | SMN1; SMN2NPC1LMNATP53PKM | |
| SCHEMBL26964564 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1LMNATP53PKM | |
| SCHEMBL30645653 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1LMNATP53PKM | |
| SCHEMBL26037839 | 0.79 | CYP3A4 (0.31) | — | |
| SCHEMBL26964795 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1LMNATP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154426-A1 | CDK INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |