Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.53 |
| ▸ | TEK | Q02763 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22557555 | 0.91 | HDAC6 (0.59) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL25348490 | 0.86 | HSP90AA1 (0.44) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL25992735 | 0.85 | HDAC6 (0.57) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL22558008 | 0.83 | HDAC6 (0.62) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL24215835 | 0.83 | HDAC6 (0.62) | HDAC6TEKKDREPHB4MEN1 | |
| SCHEMBL25350331 | 0.83 | HDAC6 (0.57) | HDAC6TEKKDREPHB4ESRRG | |
| SCHEMBL25244262 | 0.82 | HDAC6 (0.61) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL24599266 | 0.82 | HDAC6 (0.61) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL25386563 | 0.81 | HDAC6 (0.60) | HDAC6HSP90AA1HSP90AB1TEKKDR | |
| SCHEMBL24216740 | 0.81 | HDAC6 (0.55) | HDAC6TEKKDREPHB4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC6, HDAC1, HDAC3 | HDAC6 1/4885HSP90AA1 153/4885HSP90AB1 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.