Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25358394 | 0.97 | BRD4 (0.38) | MAOBBRD4HRH4HTR2CHSD11B1 | |
| SCHEMBL25353405 | 0.97 | BRD4 (0.38) | MAOBBRD4HRH4HTR2CHSD11B1 | |
| SCHEMBL23222196 | 0.89 | MAOB (0.39) | MAOBBRD4HRH4HTR2CHSD11B1 | |
| SCHEMBL19002463 | 0.83 | EPHX2 (0.42) | BRD4HRH4 | |
| SCHEMBL18997553 | 0.83 | BRD4 (0.39) | BRD4HRH4HTR2CHSD11B1AVPR1A | |
| SCHEMBL27520764 | 0.81 | GSK3B (0.43) | HRH4SIGMAR1 | |
| SCHEMBL21105408 | 0.81 | GSK3B (0.43) | BRD4HDAC4SIGMAR1CYP1A2 | |
| SCHEMBL27224078 | 0.81 | GSK3B (0.43) | BRD4HDAC4SIGMAR1ALDH1A1HTT | |
| SCHEMBL30453849 | 0.81 | MAPK1 (0.48) | — | |
| SCHEMBL30453635 | 0.81 | MAPK1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |