Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576899 | 1.00 | KRAS (0.42) | KRAS | |
| SCHEMBL30576954 | 0.95 | KRAS (0.39) | KRAS | |
| SCHEMBL25352938 | 0.94 | KRAS (0.44) | KRAS | |
| SCHEMBL30576902 | 0.92 | KRAS (0.39) | KRAS | |
| SCHEMBL25354678 | 0.92 | KRAS (0.39) | KRAS | |
| SCHEMBL30576963 | 0.90 | KRAS (0.42) | KRAS | |
| SCHEMBL25994231 | 0.90 | KRAS (0.41) | KRAS | |
| SCHEMBL30576893 | 0.90 | KRAS (0.41) | KRAS | |
| SCHEMBL30576896 | 0.90 | KRAS (0.41) | KRAS | |
| SCHEMBL30576937 | 0.89 | KRAS (0.41) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152255-A1 | FUSED PYRIMIDINES AS KRAS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023152255-A1 | FUSED PYRIMIDINES AS KRAS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-17 | — | — | WO | disclosed |