Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25359569 | 0.92 | OPRL1 (0.35) | OPRL1RORC | |
| SCHEMBL25356543 | 0.92 | OPRL1 (0.37) | OPRL1RORC | |
| SCHEMBL25358043 | 0.89 | OPRL1 (0.37) | OPRL1RORC | |
| SCHEMBL25355295 | 0.89 | OPRL1 (0.40) | OPRL1 | |
| SCHEMBL25357190 | 0.89 | OPRL1 (0.40) | OPRL1 | |
| SCHEMBL25361816 | 0.87 | OPRL1 (0.35) | OPRL1RORC | |
| SCHEMBL25358584 | 0.87 | OPRL1 (0.35) | OPRL1RORC | |
| SCHEMBL25358272 | 0.87 | OPRL1 (0.35) | OPRL1RORC | |
| SCHEMBL31387422 | 0.86 | JAK2 (0.36) | OPRL1RORC | |
| SCHEMBL26066260 | 0.86 | JAK2 (0.36) | OPRL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |