SCHEMBL25358993

SCHEMBL25358993

O=S(=O)(Cl)c1c(F)c(F)cc(F)c1Br

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.48
CA2 P00918 8/20 0.48
CA12 O43570 1/20 0.48
CA7 P43166 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
CA9 Q16790 3/20 0.32
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022230 0.86 CA1 (0.38) CA1CA2CA12CA7CA13
SCHEMBL4502132 0.84 CA1 (0.58) CA1CA2CA12CA7CA13
SCHEMBL29668992 0.83 CA12 (0.39) CA1CA2CA12CA7CA13
SCHEMBL19613260 0.83 CA12 (0.39) CA1CA2CA12CA7CA13
SCHEMBL25357619 0.79 CA1 (0.48) CA1CA2CA12CA7CA13
SCHEMBL20237716 0.76 CA1 (0.48) CA1CA2CA12CA7CA13
SCHEMBL29505942 0.76 CA1 (0.48) CA1CA2CA12CA7CA13
SCHEMBL25357808 0.75 CA1 (0.43) CA1CA2CA12CA7CA13
SCHEMBL6676829 0.73 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL29505948 0.73 CA1 (0.40) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265055-A1 STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS OXFORD FINANCE LLC 2023-08-24 US disclosed
WO-2022051639-A1 STAT INHIBITORY COMPOUNDS AND COMPOSITIONS JANPIX LIMITED (US) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265055-A1 STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS STAT5B, STAT5A, STAT3 CA1 4704/4885CA2 4486/4885CA12 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.