SCHEMBL2535941

SCHEMBL2535941

Cc1ccc(Nc2ccc(C)cc2)cc1.Ic1cccc(I)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.58
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
GAA P10253 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
G6PD P11413 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAPT P10636 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
APP P05067 2/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
SNCA P37840 1/20 0.40
ALDH1A1 P00352 2/20 0.39
AR P10275 1/20 0.39
EGFR P00533 1/20 0.39
KDM1A O60341 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24570954 0.83 HPGD (0.59) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL23734738 0.81 HPGD (0.61) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL1685626 0.79 HPGD (0.73) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL108881 0.78 HPGD (0.78) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL50079 0.78 HPGD (0.78) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL9516537 0.78 HPGD (0.78) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL3373557 0.76 GAA (0.67) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL11502241 0.76 NPSR1 (0.79) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL3040701 0.76 NPSR1 (0.79) HPGDMEN1KMT2AGAAL3MBTL1
Water SCHEMBL8602751 0.75 HPGD (0.74) HPGDMEN1KMT2AGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8043723-B2 Organic EL device with organic layer including starburst compound DENSO CORPORATION (JP) 2011-10-25 US disclosed
US-20070224449-A1 Organic EL device DENSO CORPORATION (JP) 2007-09-27 US disclosed