Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.59 |
| ▸ | BRD2 | P25440 | 2/20 | 0.52 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536530 | 0.95 | BRD4 (0.57) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2538525 | 0.95 | BRD4 (0.57) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2540552 | 0.94 | BRD4 (0.54) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2540549 | 0.94 | BRD4 (0.54) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2539552 | 0.93 | BRD4 (0.56) | BRD4BRD2BRDTBRD3 | |
| SCHEMBL2539555 | 0.93 | BRD4 (0.56) | BRD4BRD2BRDTBRD3 | |
| SCHEMBL2543006 | 0.92 | BRD4 (0.69) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2543001 | 0.92 | BRD4 (0.69) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2538963 | 0.92 | BRD4 (0.54) | BRD4BRD2BRDTBRD3ADORA3 | |
| SCHEMBL2538091 | 0.91 | BRD4 (0.60) | BRD4BRD2BRDTBRD3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044042-B2 | Thienotriazolodiazepine compound and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |