SCHEMBL25360536

SCHEMBL25360536

Cn1cnnc1CC1(c2cccc(NC(=O)c3cc(CN4CCCC(C(F)(F)F)C4)c4c(n3)C(C)(C)CC4)c2)COC1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25360332 0.92 CBLB (0.59) CBLB
SCHEMBL25364530 0.90 CBLB (0.58) CBLB
SCHEMBL25361732 0.88 CBLB (0.61) CBLB
SCHEMBL25359001 0.87 CBLB (0.72) CBLB
SCHEMBL31578410 0.86 CBLB (0.57) CBLB
SCHEMBL25361200 0.86 CBLB (0.52) CBLB
SCHEMBL25361714 0.85 CBLB (0.51) CBLB
SCHEMBL31578179 0.83 CBLB (0.59) CBLB
SCHEMBL25360070 0.82 CBLB (0.60) CBLB
SCHEMBL25361481 0.81 CBLB (0.56) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023151642-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 — — WO disclosed
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