SCHEMBL25360549 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CCNK	O75909	18/20	0.51

▸	CDK12	Q9NYV4	18/20	0.51

▸	CCNT1	O60563	16/20	0.51

▸	CDK9	P50750	16/20	0.51

▸	CCNE1	P24864	15/20	0.51

▸	CDK2	P24941	15/20	0.51

▸	CDK7	P50613	9/20	0.51

▸	CCNH	P51946	9/20	0.51

▸	MNAT1	P51948	6/20	0.51

▸	CYP2D6	P10635	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30456342	1.00	CCNK (0.51)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL25362763	0.97	CCNK (0.51)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL30455872	0.97	CCNK (0.51)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL30456284	0.96	CCNK (0.51)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL25363350	0.96	CCNK (0.51)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL25363347	0.96	CCNK (0.51)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL30456173	0.90	CDK7 (0.48)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL25362356	0.90	CDK7 (0.48)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL25366226	0.90	CCNK (0.47)	CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL30457380	0.90	CCNK (0.47)	CCNKCDK12CCNT1CDK9CCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023116761-A1	PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE	英矽智能科技知识产权有限公司	2023-06-29	—	—	WO	disclosed