Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496077 | 1.00 | SIRT2 (0.51) | SIRT2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL26025076 | 0.94 | PTPN2 (0.54) | SIRT2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30496051 | 0.94 | PTPN2 (0.54) | SIRT2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL25362245 | 0.94 | PTPN2 (0.54) | SIRT2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL26911374 | 0.89 | SIRT2 (0.48) | SIRT2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30496080 | 0.88 | PTPN2 (0.60) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7714103 | 0.88 | PTPN2 (0.60) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19378084 | 0.87 | HDAC1 (0.62) | KMT2AMEN1ALDH1A1ABL1RIN1 | |
| SCHEMBL762580 | 0.87 | HDAC1 (0.62) | KMT2AMEN1ALDH1A1ABL1RIN1 | |
| SCHEMBL17533942 | 0.87 | HDAC1 (0.62) | KMT2AMEN1ALDH1A1ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |