Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22636071 | 1.00 | ACE (0.31) | ACE | |
| SCHEMBL8295119 | 0.81 | ACE (0.31) | ACE | |
| SCHEMBL12741725 | 0.81 | ACE (0.31) | ACE | |
| SCHEMBL28777416 | 0.81 | KLK7 (0.31) | — | |
| SCHEMBL18241829 | 0.79 | — | — | |
| SCHEMBL8294058 | 0.71 | TP53 (0.33) | ACE | |
| SCHEMBL25191423 | 0.71 | ACE (0.36) | ACE | |
| SCHEMBL25191422 | 0.71 | ACE (0.36) | ACE | |
| SCHEMBL10138505 | 0.70 | MAPK1 (0.32) | — | |
| SCHEMBL12604934 | 0.70 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |