Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | ESRRG | P62508 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | CASP1 | P29466 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243886 | 1.00 | MAPT (0.76) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12735427 | 0.87 | MAPT (0.82) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL12937859 | 0.86 | MAPT (0.69) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13497013 | 0.86 | ESRRG (0.74) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9755112 | 0.86 | ESRRG (0.74) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1131313 | 0.86 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1129782 | 0.86 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1131315 | 0.86 | MAPT (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15315413 | 0.85 | MAPT (0.79) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15315410 | 0.85 | ESRRG (1.00) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044241-B2 | Ligands for estrogen related receptors and methods for synthesis of said ligands | CITY OF HOPE (US) | 2011-10-25 | — | — | US | disclosed |