SCHEMBL25369

SCHEMBL25369

[CH2]C(F)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837597 0.72
SCHEMBL9520974 0.71
SCHEMBL14127280 0.70
SCHEMBL30733 0.70
SCHEMBL3491593 0.68
SCHEMBL1040886 0.67
SCHEMBL84473 0.67
SCHEMBL11659736 0.67
SCHEMBL3156496 0.67
SCHEMBL21828481 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4269 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043674-B2 Synthetic cyclic peptides and methods of preparation and use thereof AUBURN UNIVERSITY (US) 2024-07-23 US disclosed
US-12042523-B2 Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof UNIGEN, INC. (US) 2024-07-23 US disclosed
WO-2024151638-A2 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-07-18 WO disclosed
WO-2024150067-A2 ACYLOIN CONDENSATION REACTIONS, ENZYMES, AND PRODUCTS THEREOF MOJIA BIOTECH PTE. LTD. (SG) 2024-07-18 WO disclosed
US-20240238285-A1 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES, INC. 2024-07-18 US disclosed
CN-118344342-A Substituted polyaromatic ring derivatives, compositions and uses thereof 康迈迪森(北京)医药科技有限公司 2024-07-16 CN disclosed
US-12036319-B2 Polyvalent sting activating compositions and uses thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-16 US disclosed
US-12037335-B2 Substituted purines as TLR7 agonists Primmune Therapeutics, Inc. (US) 2024-07-16 US disclosed
US-12036292-B2 Heterobiaryl compounds and imaging agents for imaging huntingtin protein CHDI FOUNDATION, INC. (US) 2024-07-16 US disclosed
CN-118339149-A Compounds and compositions for treating conditions associated with LPA receptor activity 罗特斯生物公司 2024-07-12 CN disclosed
US-5693641-A ENZYME INHIBITOR TREATING BLOOD DISORDER BERLEX LABORATORIES INC. (US) 1997-12-02 US disclosed
US-5691364-A Benzamidine derivatives and their use as anti-coagulants BERLEX LABORATORIES, INC. (US) 1997-11-25 US disclosed
WO-1997029067-A1 BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS BERLEX LABORATORIES, INC. (DE) 1997-08-14 WO disclosed
US-5612363-A FACTOR XA INHIBITORS BERLEX LABORATORIES, INC. (US) 1997-03-18 US disclosed
WO-1996028427-A1 BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS BERLEX LABORATORIES, INC. (US) 1996-09-19 WO disclosed
CN-1024669-C Process for preparing cephem compounds TIKOSAWA PHARMACEUTICAL CO LTD (JP) 1994-05-25 CN disclosed
EP-0307804-B1 Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1993-11-18 EP disclosed
US-4952578-A Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-08-28 US disclosed
CN-1032540-A Cephem compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1989-04-26 CN disclosed
EP-0307804-A2 Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-03-22 EP disclosed