SCHEMBL25369148

SCHEMBL25369148

NC(=O)C(Cc1ccccc1)NC(=O)c1nn(Cc2ccc(F)cc2)c2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 7/20 0.71
▸ CNR2 P34972 4/20 0.68
▸ PTGER4 P35408 9/20 0.60
▸ PTGS1 P23219 1/20 0.48
▸ PTGS2 P35354 1/20 0.48
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12884556 1.00 CNR1 (0.71) CNR1CNR2PTGER4PTGS1PTGS2
SCHEMBL12884874 0.90 CNR1 (0.66) CNR1CNR2PTGER4
SCHEMBL12884869 0.87 CNR1 (0.67) CNR1CNR2PTGER4MEN1KMT2A
SCHEMBL25368006 0.87 CNR1 (0.72) CNR1CNR2PTGER4PTGS1PTGS2
SCHEMBL1217138 0.85 CNR1 (0.72) CNR1CNR2PTGER4PTGS1PTGS2
SCHEMBL27823781 0.85 CNR1 (0.72) CNR1CNR2PTGER4PTGS1PTGS2
SCHEMBL12884886 0.83 CNR1 (0.67) CNR1CNR2PTGER4KMT2A
SCHEMBL29362171 0.83 CNR1 (1.00) CNR1CNR2PTGER4PTGS1PTGS2
SCHEMBL1217062 0.83 CNR1 (1.00) CNR1CNR2PTGER4PTGS1PTGS2
SCHEMBL16201827 0.83 CNR1 (1.00) CNR1CNR2PTGER4PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES PASCAL BIOSCIENCES INC (CA) 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES CNR1, CNR2, SARS1 CNR1 1/4885CNR2 2/4885PTGER4 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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