Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 17/20 | 0.63 |
| ▸ | JAK1 | P23458 | 17/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18685106 | 0.89 | JAK1 (0.69) | JAK2JAK1 | |
| SCHEMBL29431103 | 0.89 | JAK1 (0.69) | JAK2JAK1 | |
| SCHEMBL30480920 | 0.87 | JAK1 (0.66) | JAK2JAK1 | |
| SCHEMBL25368326 | 0.87 | JAK1 (0.66) | JAK2JAK1 | |
| SCHEMBL29466936 | 0.85 | JAK1 (0.62) | JAK2JAK1 | |
| SCHEMBL30756723 | 0.81 | JAK1 (0.46) | JAK2JAK1 | |
| SCHEMBL26987136 | 0.81 | JAK1 (0.46) | JAK2JAK1 | |
| SCHEMBL27030917 | 0.80 | CLK1 (0.53) | JAK2JAK1 | |
| SCHEMBL24474852 | 0.80 | JAK1 (0.65) | JAK2JAK1 | |
| SCHEMBL24474853 | 0.79 | JAK1 (0.65) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353168-B1 | COMPOUNDS AND METHODS FOR INHIBITING JAK | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| EP-4219482-A1 | COMPOUNDS AND METHODS FOR INHIBITING JAK | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-08-02 | — | — | EP | disclosed |