Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 13/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438575 | 1.00 | F9 (0.51) | F9PIK3CAMTORPIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL1439422 | 0.99 | F9 (0.51) | F9PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL2534642 | 0.95 | F9 (0.50) | F9PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL1950684 | 0.95 | F9 (0.50) | F9PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL1438648 | 0.94 | F9 (0.48) | F9PIK3CAMTORPIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL1950483 | 0.94 | F9 (0.49) | F9PIK3CAMTORPIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL1444418 | 0.94 | F9 (0.48) | F9PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL1948275 | 0.90 | F9 (0.49) | F9PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL1948837 | 0.90 | F9 (0.49) | F9PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL1950302 | 0.90 | F9 (0.57) | F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | Mochida Pharmaceutical Co., Ltd. (JP) | 2011-10-12 | — | — | EP | claimed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | claimed |