Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 4/20 | 0.59 |
| ▸ | PAK1 | Q13153 | 4/20 | 0.59 |
| ▸ | IGF1R | P08069 | 7/20 | 0.48 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | YES1 | P07947 | 1/20 | 0.44 |
| ▸ | HCK | P08631 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371006 | 1.00 | PAK4 (0.59) | PAK4PAK1IGF1RNEK1SRC | |
| SCHEMBL25370869 | 0.97 | PAK4 (0.55) | PAK4PAK1IGF1RNEK1SRC | |
| SCHEMBL25370485 | 0.95 | PAK4 (0.64) | PAK4PAK1IGF1RNEK1SRC | |
| SCHEMBL25372498 | 0.89 | PAK4 (0.66) | PAK4PAK1IGF1RNEK1AURKA | |
| SCHEMBL30558772 | 0.89 | PAK4 (0.66) | PAK4PAK1IGF1RNEK1AURKA | |
| SCHEMBL30558779 | 0.89 | PAK4 (0.66) | PAK4PAK1IGF1RNEK1AURKA | |
| SCHEMBL25370283 | 0.89 | PAK4 (0.66) | PAK4PAK1IGF1RNEK1AURKA | |
| SCHEMBL25370276 | 0.89 | PAK4 (0.66) | PAK4PAK1IGF1RNEK1AURKA | |
| SCHEMBL25371712 | 0.89 | PAK4 (0.54) | PAK4PAK1IGF1RSRCABL1 | |
| SCHEMBL25368580 | 0.89 | PAK4 (0.54) | PAK4PAK1IGF1RSRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163712-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164611-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |