Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.60 |
| ▸ | KDR | P35968 | 8/20 | 0.56 |
| ▸ | FLT1 | P17948 | 5/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.56 |
| ▸ | FLT4 | P35916 | 3/20 | 0.56 |
| ▸ | RET | P07949 | 3/20 | 0.52 |
| ▸ | KIF5B | P33176 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 7/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.52 |
| ▸ | CIT | O14578 | 2/20 | 0.52 |
| ▸ | GAK | O14976 | 2/20 | 0.52 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.52 |
| ▸ | STK17B | O94768 | 2/20 | 0.52 |
| ▸ | STK10 | O94804 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | LYN | P07948 | 2/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | HCK | P08631 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30429677 | 1.00 | EGFR (0.60) | EGFRKDRFLT1FGFR1FLT4 | |
| SCHEMBL29380812 | 0.88 | EGFR (0.57) | EGFRKDRFLT1FGFR1FLT4 | |
| SCHEMBL25212340 | 0.88 | EGFR (0.57) | EGFRKDRFLT1FGFR1FLT4 | |
| SCHEMBL25244478 | 0.85 | EGFR (0.69) | EGFRKDRFLT1RETSRC | |
| SCHEMBL29380830 | 0.85 | EGFR (0.69) | EGFRKDRFLT1RETSRC | |
| SCHEMBL25372443 | 0.82 | EGFR (0.64) | EGFRKDRFLT1RETSRC | |
| SCHEMBL30429601 | 0.82 | EGFR (0.64) | EGFRKDRFLT1RETSRC | |
| SCHEMBL3245680 | 0.81 | EGFR (0.66) | EGFRKDRFLT1FGFR1FLT4 | |
| SCHEMBL25663079 | 0.80 | EGFR (0.58) | EGFRKDRFLT1FLT4RET | |
| SCHEMBL26055604 | 0.79 | EGFR (0.69) | EGFRKDRFLT1RETSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271936-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271936-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271936-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| EP-4194443-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| EP-4194443-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271936-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | EGFR, WEE1, WEE2 | EGFR 1/4885KDR 33/4885FLT1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.