Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.51 |
| ▸ | BRD2 | P25440 | 2/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537228 | 1.00 | BRD4 (0.51) | BRD4BRD2BRDT | |
| SCHEMBL2538981 | 0.87 | BRD4 (0.51) | BRD4BRD2BRDT | |
| SCHEMBL2538986 | 0.87 | BRD4 (0.51) | BRD4BRD2BRDT | |
| SCHEMBL3215682 | 0.87 | BRD4 (0.61) | BRD4BRD2BRDT | |
| SCHEMBL2537126 | 0.87 | BRD4 (0.59) | BRD4BRD2BRDT | |
| SCHEMBL2537129 | 0.87 | BRD4 (0.59) | BRD4BRD2BRDT | |
| SCHEMBL2545011 | 0.86 | BRD4 (0.54) | BRD4BRD2BRDT | |
| SCHEMBL2545315 | 0.86 | BRD4 (0.54) | BRD4BRD2BRDT | |
| SCHEMBL2538951 | 0.86 | BRD4 (0.60) | BRD4BRDT | |
| SCHEMBL2538956 | 0.86 | BRD4 (0.60) | BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044042-B2 | Thienotriazolodiazepine compound and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |