Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377502 | 0.84 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL25376034 | 0.80 | AAK1 (0.37) | CYP2C19CYP3A4CYP2C9PKM | |
| SCHEMBL25378007 | 0.78 | PIK3CB (0.40) | CYP2C19ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL21392141 | 0.75 | ANO1 (0.39) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 | |
| SCHEMBL30882869 | 0.75 | CYP2C19 (0.38) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 | |
| SCHEMBL28476061 | 0.75 | CYP2C19 (0.38) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 | |
| SCHEMBL29551162 | 0.73 | TSHR (0.42) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 | |
| SCHEMBL3900008 | 0.73 | HDAC1 (0.39) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 | |
| SCHEMBL9966412 | 0.73 | TSHR (0.42) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 | |
| SCHEMBL21392151 | 0.73 | FFAR4 (0.37) | CYP2C19CYP3A4CYP2C9PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132650-B1 | DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2024-06-12 | — | — | EP | disclosed |
| US-20230271951-A1 | DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2023-08-31 | — | — | US | disclosed |
| CN-115702024-A | Difluorocyclohexyl derivatives as IL-17 modulators | UCB生物制药有限责任公司 | 2023-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271951-A1 | DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS | IL17A, IL2, IL23R | CYP2C19 696/4885CYP3A4 1115/4885CYP2C9 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.