SCHEMBL25375360

SCHEMBL25375360

CCCCN1CC(C)(C)O[Sn]2(OC(C)(C)C1)OC(C)(C)CN(CCCC)CC(C)(C)O2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLB1 P16278 1/20 0.34
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
S1PR5 Q9H228 2/20 0.33
S1PR4 O95977 1/20 0.33
SIGMAR1 Q99720 2/20 0.32
EBP Q15125 1/20 0.32
MAPK1 P28482 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31
HTR2A P28223 1/20 0.31
SCN1A P35498 1/20 0.31
HTR2B P41595 1/20 0.31
KCNH2 Q12809 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
GBA1 P04062 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25372404 0.85 MAPK1 (0.35) S1PR1S1PR3S1PR5S1PR4SIGMAR1
SCHEMBL25374705 0.83 MAPK1 (0.36) S1PR1S1PR3S1PR5S1PR4SIGMAR1
SCHEMBL25374220 0.82 EBP (0.41) GLB1SIGMAR1EBPGBA1
SCHEMBL25373345 0.81 MAPK1 (0.38) S1PR1S1PR3S1PR5S1PR4SIGMAR1
SCHEMBL25406058 0.78 S1PR1 (0.36) S1PR1S1PR3S1PR5S1PR4SIGMAR1
SCHEMBL25407519 0.77 S1PR1 (0.38) S1PR1S1PR3S1PR5S1PR4SIGMAR1
SCHEMBL25406509 0.77 S1PR1 (0.38) S1PR1S1PR3S1PR5S1PR4SIGMAR1
SCHEMBL11135474 0.71 S1PR1 (0.38) GLB1S1PR1S1PR3S1PR5S1PR4
SCHEMBL25404337 0.71
SCHEMBL28803699 0.70 CYP2D6 (0.50) GLB1S1PR1S1PR3S1PR5S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4234602-A1 USE OF SPECIAL CATALYSTS FOR THE PREPARATION OF POLYURETHANE COATINGS Covestro Deutschland AG (DE) 2023-08-30 EP disclosed