Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376279 | 1.00 | TLR8 (0.43) | TLR8TLR7KCNH2NLRP3CYP2D6 | |
| SCHEMBL25374007 | 0.93 | TLR8 (0.46) | TLR8TLR7KCNH2NLRP3 | |
| SCHEMBL25374022 | 0.93 | TLR8 (0.46) | TLR8TLR7KCNH2NLRP3 | |
| SCHEMBL30570468 | 0.90 | TLR8 (0.48) | TLR8TLR7KCNH2NLRP3CYP2D6 | |
| SCHEMBL25373861 | 0.90 | TLR8 (0.48) | TLR8TLR7KCNH2NLRP3CYP2D6 | |
| SCHEMBL29063534 | 0.89 | TLR8 (0.47) | TLR8TLR7KCNH2NLRP3DHFR | |
| SCHEMBL29063543 | 0.89 | TLR8 (0.47) | TLR8TLR7KCNH2NLRP3DHFR | |
| SCHEMBL25439259 | 0.88 | TLR8 (0.45) | TLR8TLR7KCNH2NLRP3DHFR | |
| SCHEMBL25374600 | 0.87 | TLR8 (0.42) | TLR8TLR7KCNH2NLRP3CYP2D6 | |
| SCHEMBL25374605 | 0.87 | TLR8 (0.42) | TLR8TLR7KCNH2NLRP3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693527-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |