Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376373 | 1.00 | TLR8 (0.58) | TLR8TLR7 | |
| SCHEMBL25375281 | 0.93 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL30563779 | 0.93 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL25375298 | 0.93 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL25375481 | 0.90 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL25375717 | 0.90 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL25375695 | 0.90 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL25377310 | 0.89 | TLR8 (0.51) | TLR8TLR7 | |
| SCHEMBL25377317 | 0.89 | TLR8 (0.51) | TLR8TLR7 | |
| SCHEMBL25377708 | 0.89 | TLR8 (0.60) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |