Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163500 | 0.89 | POLB (0.56) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL30552687 | 0.84 | POLB (0.59) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL25431128 | 0.84 | POLB (0.59) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL31428828 | 0.81 | POLB (0.59) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL31428559 | 0.80 | POLB (0.56) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL3369566 | 0.74 | HRH4 (0.59) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL18889291 | 0.74 | HRH4 (0.76) | POLBSMN1; SMN2HRH3KMT2AMEN1 | |
| SCHEMBL2770082 | 0.72 | HRH4 (0.71) | POLBSMN1; SMN2HRH3KMT2AHRH4 | |
| SCHEMBL3253717 | 0.71 | POLB (1.00) | POLBSMN1; SMN2HRH3HRH4 | |
| SCHEMBL2768817 | 0.71 | HRH3 (0.76) | POLBSMN1; SMN2HRH3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482583-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161316-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-31 | — | — | WO | disclosed |