Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248311 | 0.88 | KDR (0.38) | FLT3TYRO3MERTKGAS6KDR | |
| SCHEMBL29099894 | 0.85 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6KDR | |
| SCHEMBL29099891 | 0.85 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6KDR | |
| SCHEMBL25377448 | 0.84 | KDR (0.37) | FLT3TYRO3MERTKGAS6KDR | |
| SCHEMBL25374138 | 0.84 | TLR8 (0.45) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL25374136 | 0.84 | TLR8 (0.45) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL30570467 | 0.83 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL25376815 | 0.83 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL25376813 | 0.83 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL25377704 | 0.83 | JAK3 (0.38) | FLT3TYRO3MERTKGAS6KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4484426-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | Sunshine Lake Pharma Co., Ltd. (CN) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |