Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563275 | 1.00 | CYP4F2 (0.48) | CYP4F2CYP4A11HDAC1LOXL2CA14 | |
| SCHEMBL30563260 | 0.91 | HDAC1 (0.45) | HDAC1CA14HDAC3HDAC2NCOR2 | |
| SCHEMBL25380568 | 0.91 | HDAC1 (0.45) | HDAC1CA14HDAC3HDAC2NCOR2 | |
| SCHEMBL5725025 | 0.84 | CYP4F2 (0.60) | CYP4F2CYP4A11LOXL2MAPTKDM4E | |
| SCHEMBL31747308 | 0.84 | CYP4F2 (0.60) | CYP4F2CYP4A11LOXL2MAPTKDM4E | |
| SCHEMBL31730134 | 0.82 | CYP4F2 (0.61) | CYP4F2CYP4A11LOXL2MAPTBRD4 | |
| SCHEMBL29347083 | 0.82 | CYP4F2 (0.61) | CYP4F2CYP4A11LOXL2MAPTBRD4 | |
| SCHEMBL30563213 | 0.81 | CA14 (0.45) | CYP4F2CYP4A11HDAC1CA14HDAC3 | |
| SCHEMBL25378075 | 0.81 | CA14 (0.45) | CYP4F2CYP4A11HDAC1CA14HDAC3 | |
| SCHEMBL8630273 | 0.81 | HDAC3 (0.52) | HDAC1CA14HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118843616-A | Benzamide compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-10-25 | — | — | CN | disclosed |
| WO-2023166103-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023166103-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | disclosed |