Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.60 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.56 |
| ▸ | FYN | P06241 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | BLK | P51451 | 1/20 | 0.56 |
| ▸ | BMX | P51813 | 1/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341768 | 0.83 | EGFR (0.78) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL12093972 | 0.83 | EGFR (0.68) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL1507476 | 0.83 | EGFR (0.80) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL2950374 | 0.82 | EGFR (0.67) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| Hydrochloric Acid SCHEMBL1507687 | 0.82 | EGFR (0.79) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL13889775 | 0.80 | EGFR (0.70) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL2949992 | 0.80 | EGFR (0.67) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL13514711 | 0.80 | EGFR (0.72) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL13514800 | 0.80 | EGFR (0.72) | EGFRHDAC3HDAC1ERBB2ERBB4 | |
| SCHEMBL1766071 | 0.80 | EGFR (0.72) | EGFRHDAC3HDAC1ERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| EP-4225122-A1 | ZWITTERIONIC CELL-PERMEANT AND WATER-SOLUBLE RHODAMINE DYES FOR QUANTITATIVE IMAGING APPLICATIONS | Oregon Health & Science University (US) | 2023-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | SLC1A5, SLCO1B1, SLCO2B1 | EGFR 1711/4885HDAC3 4283/4885HDAC1 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.