Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.42 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436553 | 0.90 | MAPK1 (0.49) | ESR2MAPTADORA1NR1H2MAPK1 | |
| SCHEMBL741598 | 0.89 | MAPK1 (0.58) | ESR2MAPTADORA1NR1H2MAPK1 | |
| SCHEMBL30916184 | 0.89 | MAPK1 (0.58) | ESR2MAPTADORA1NR1H2MAPK1 | |
| SCHEMBL30740130 | 0.87 | MAPK1 (0.45) | ESR2MAPTADORA1NR1H2MAPK1 | |
| SCHEMBL14970397 | 0.80 | MAPK1 (0.51) | MAPTMAPK1KDM4EGRM5 | |
| SCHEMBL30861099 | 0.78 | MAPK1 (0.52) | MAPK1KDM4EGRM5 | |
| SCHEMBL16219030 | 0.76 | MAPK1 (0.48) | MAPTMAPK1GRM5P2RX3 | |
| SCHEMBL19549675 | 0.76 | ADORA1 (0.48) | ESR2MAPTADORA1NR1H2KDM4E | |
| SCHEMBL19019830 | 0.76 | DDB1 (0.39) | ESR2MAPTNR1H2MAPK1KDM4E | |
| SCHEMBL27327040 | 0.76 | ADORA1 (0.48) | ESR2MAPTADORA1NR1H2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165551-A1 | SIX-MEMBERED AROMATIC RING-PYRROLIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |