SCHEMBL25397265

SCHEMBL25397265

O=C(Nc1ccc(C(=O)O)cc1NC(=O)OCC1c2ccccc2-c2ccccc21)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.56
KMT2A Q03164 4/20 0.50
POLB P06746 1/20 0.44
FABP7 O15540 2/20 0.43
FABP5 Q01469 2/20 0.43
CASP3 P42574 2/20 0.43
MEN1 O00255 2/20 0.41
NPC1 O15118 1/20 0.41
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30522780 1.00 EPHX2 (0.56) EPHX2KMT2APOLBFABP7FABP5
SCHEMBL26628373 0.93 EPHX2 (0.52) EPHX2KMT2APOLBFABP7FABP5
SCHEMBL29547060 0.93 EPHX2 (0.52) EPHX2KMT2APOLBFABP7FABP5
SCHEMBL29546978 0.93 EPHX2 (0.52) EPHX2KMT2APOLBFABP7FABP5
SCHEMBL3209189 0.90 EPHX2 (0.54) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL3214751 0.90 EPHX2 (0.57) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL3209502 0.90 EPHX2 (0.57) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL31423769 0.89 EPHX2 (0.53) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL29547309 0.89 EPHX2 (0.53) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL14701886 0.89 EPHX2 (0.53) EPHX2KMT2AFABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119173278-A Antibody-conjugated drugs and uses thereof 维硕公司 2024-12-20 CN disclosed
WO-2023173026-A1 ANTIBODY-DRUG CONJUGATES AND USES THEREOF SORRENTO THERAPEUTICS, INC. (US) 2023-09-14 WO disclosed