Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 17/20 | 0.72 |
| ▸ | EGFR | P00533 | 8/20 | 0.72 |
| ▸ | SRC | P12931 | 11/20 | 0.70 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.70 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.70 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.70 |
| ▸ | WEE1 | P30291 | 2/20 | 0.69 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.67 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.67 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.67 |
| ▸ | ABL1 | P00519 | 5/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.62 |
| ▸ | KIT | P10721 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30618362 | 1.00 | FGFR1 (0.72) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL30618274 | 0.91 | FGFR1 (0.72) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL30618267 | 0.91 | FGFR1 (0.72) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL25398991 | 0.91 | FGFR1 (0.72) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL25399633 | 0.91 | FGFR1 (0.72) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| Formic Acid SCHEMBL30618335 | 0.90 | WEE1 (0.60) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL25435326 | 0.90 | FGFR1 (0.71) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL30618250 | 0.90 | FGFR1 (0.71) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL25435935 | 0.89 | FGFR1 (0.70) | FGFR1EGFRSRCPDGFRBPDGFRA | |
| SCHEMBL30618248 | 0.89 | FGFR1 (0.70) | FGFR1EGFRSRCPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |