Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 17/20 | 0.63 |
| ▸ | SRC | P12931 | 12/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.62 |
| ▸ | ABL1 | P00519 | 6/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.62 |
| ▸ | EGFR | P00533 | 11/20 | 0.62 |
| ▸ | KIT | P10721 | 1/20 | 0.61 |
| ▸ | WEE1 | P30291 | 2/20 | 0.60 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.60 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.60 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30618344 | 1.00 | FGFR1 (0.63) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL25400152 | 0.91 | FGFR1 (0.71) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL30618320 | 0.90 | FGFR1 (0.62) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL25434100 | 0.90 | FGFR1 (0.62) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL30618273 | 0.88 | FGFR1 (0.60) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL25398684 | 0.88 | FGFR1 (0.60) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL30618285 | 0.88 | FGFR1 (0.73) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL25398666 | 0.88 | FGFR1 (0.73) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL25397614 | 0.87 | FGFR1 (0.57) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL30618298 | 0.87 | FGFR1 (0.57) | FGFR1SRCPDGFRBPDGFRAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177356-A2 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-09-21 | — | — | WO | disclosed |