Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 3/20 | 0.52 |
| ▸ | RAC2 | P15153 | 1/20 | 0.50 |
| ▸ | RAC3 | P60763 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683260 | 0.85 | RAC1 (0.51) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL20678041 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL20683281 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL4146513 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL25405308 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL31121075 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL20678119 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL25402058 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL31121063 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 | |
| SCHEMBL4167757 | 0.84 | RAC1 (0.54) | RAC1RAC2RAC3ADRB2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742539-A | Heterocyclic derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023169391-A1 | HETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-09-14 | — | — | WO | disclosed |