Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083707 | 1.00 | MAPT (0.48) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25405037 | 0.88 | TRPV1 (0.48) | MAPTTRPV1NPC1RAB9ACDK4 | |
| SCHEMBL31083742 | 0.88 | TRPV1 (0.48) | MAPTTRPV1NPC1RAB9ACDK4 | |
| SCHEMBL30593244 | 0.87 | KDM4E (0.49) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25405602 | 0.87 | KDM4E (0.49) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25406123 | 0.81 | KDM4E (0.49) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30593220 | 0.81 | KDM4E (0.49) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25405345 | 0.80 | TAAR1 (0.50) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25404212 | 0.80 | TAAR1 (0.50) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30593303 | 0.80 | TAAR1 (0.50) | MAPTTRPV1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023174383-A1 | DIHYDROISOQUINOLINE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-09-21 | — | — | WO | disclosed |