Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 2/20 | 0.45 |
| ▸ | SKP1 | P63208 | 2/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447089 | 0.86 | NR1H2 (0.53) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL29665792 | 0.83 | NR1H2 (0.51) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL265716 | 0.83 | NR1H2 (0.51) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL31121084 | 0.81 | SMARCA2 (0.54) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL25402115 | 0.81 | SMARCA2 (0.54) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL34466226 | 0.80 | MAPT (0.49) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL13419741 | 0.80 | MAPT (0.49) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL29569426 | 0.79 | NR1H2 (0.54) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL29508821 | 0.79 | MAPT (0.55) | SMARCA2SMARCA4PBRM1NR1H2GPR119 | |
| SCHEMBL993225 | 0.79 | MAPT (0.55) | SMARCA2SMARCA4PBRM1NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169391-A1 | HETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-09-14 | — | — | WO | disclosed |