Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406923 | 0.91 | CSF1R (0.63) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL26271759 | 0.91 | CSF1R (0.75) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL26272705 | 0.88 | CSF1R (0.63) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL25406556 | 0.83 | CSF1R (0.60) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL25404649 | 0.83 | CSF1R (0.76) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL26273655 | 0.83 | PDGFRB (0.73) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL25406294 | 0.82 | PDGFRB (0.61) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL26270863 | 0.81 | PDGFRB (0.72) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL26271694 | 0.81 | PDGFRB (0.68) | CSF1RPDGFRBPDGFRAKDRNTRK1 | |
| SCHEMBL26275106 | 0.80 | PDGFRB (0.70) | CSF1RPDGFRBPDGFRAKDRNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173480-A1 | SELECTIVE CSF1R INHIBITOR AND USE THEREOF | 中国科学院合肥物质科学研究院 | 2023-09-21 | — | — | WO | disclosed |
| WO-2023173480-A1 | SELECTIVE CSF1R INHIBITOR AND USE THEREOF | 中国科学院合肥物质科学研究院 | 2023-09-21 | — | — | WO | disclosed |