Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.67 |
| ▸ | CCKBR | P32239 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410241 | 1.00 | CHRM1 (0.67) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL31366551 | 1.00 | CHRM1 (0.67) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL25410235 | 1.00 | CHRM1 (0.67) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL25409166 | 0.92 | CHRM1 (0.79) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL31366536 | 0.92 | CHRM1 (0.79) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL25409170 | 0.92 | CHRM1 (0.79) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL25410981 | 0.92 | CHRM1 (0.79) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL25411673 | 0.82 | CHRM1 (0.64) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL25411668 | 0.82 | CHRM1 (0.64) | CHRM1CCKBRMEN1LMNAALB | |
| SCHEMBL31366548 | 0.82 | CHRM1 (0.64) | CHRM1CCKBRMEN1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE | 2025-06-19 | — | — | US | disclosed |
| WO-2023172726-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE (US) | 2023-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | CUL4B, BRD4, CUL4A | CHRM1 4419/4885CCKBR 3175/4885MEN1 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.