Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.61 |
| ▸ | ELOC | Q15369 | 4/20 | 0.51 |
| ▸ | ELOB | Q15370 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25411369 | 1.00 | VHL (0.61) | VHLELOCELOB | |
| SCHEMBL25411363 | 1.00 | VHL (0.61) | VHLELOCELOB | |
| SCHEMBL25413091 | 1.00 | VHL (0.61) | VHLELOCELOB | |
| SCHEMBL31297445 | 0.92 | VHL (0.59) | VHLELOCELOB | |
| SCHEMBL30843443 | 0.91 | VHL (0.67) | VHLELOCELOB | |
| SCHEMBL31398422 | 0.91 | VHL (0.67) | VHLELOCELOB | |
| SCHEMBL30760040 | 0.87 | VHL (0.46) | VHLELOCELOB | |
| SCHEMBL30760018 | 0.86 | VHL (0.46) | VHLELOCELOB | |
| SCHEMBL30760137 | 0.86 | VHL (0.46) | VHLELOCELOB | |
| SCHEMBL30760102 | 0.86 | VHL (0.44) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024034123-A1 | PHARMACEUTICAL COMPOSITION CONTAINING HETEROCYCLIC COMPOUND | アステラス製薬株式会社 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024034657-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HETEROCYCLIC COMPOUND | アステラス製薬株式会社 | 2024-02-15 | — | — | WO | disclosed |
| WO-2023171781-A1 | HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12D MUTANT KRAS PROTEIN | アステラス製薬株式会社 | 2023-09-14 | — | — | WO | disclosed |
| WO-2022173032-A1 | QUINAZOLINE COMPOUND FOR INDUCING DEGRADATION OF G12D-MUTATION KRAS PROTEIN | アステラス製薬株式会社 | 2022-08-18 | — | — | WO | disclosed |