Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | FAAH | O00519 | 7/20 | 0.45 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25413152 | 1.00 | PTGS1 (0.52) | PTGS1PTGS2FAAHMGLLSMN1; SMN2 | |
| SCHEMBL17347452 | 0.95 | PTGS1 (0.44) | PTGS1PTGS2FAAHMGLLSMN1; SMN2 | |
| SCHEMBL12287624 | 0.95 | PTGS1 (0.58) | PTGS1PTGS2FAAHMGLLSMN1; SMN2 | |
| SCHEMBL14660025 | 0.95 | PTGS1 (0.58) | PTGS1PTGS2FAAHMGLLSMN1; SMN2 | |
| SCHEMBL26645911 | 0.89 | KDM4E (0.44) | PTGS1PTGS2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL26645910 | 0.89 | KDM4E (0.44) | PTGS1PTGS2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28998100 | 0.89 | PTGS1 (0.41) | PTGS1PTGS2FAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL25331601 | 0.89 | PTGS1 (0.49) | PTGS1PTGS2FAAHMGLLSMN1; SMN2 | |
| SCHEMBL24983429 | 0.89 | PTGS1 (0.49) | PTGS1PTGS2FAAHMGLLSMN1; SMN2 | |
| SCHEMBL20485990 | 0.89 | PTGS1 (0.40) | PTGS1PTGS2FAAHSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304563-A1 | ACTIVATORS OF EFFECTOR T CELLS | ORUM THERAPEUTICS, INC. (KR) | 2025-10-02 | — | — | US | disclosed |
| EP-4490152-A1 | ACTIVATORS OF EFFECTOR T CELLS | Orum Therapeutics Inc. (KR) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023170608-A1 | ACTIVATORS OF EFFECTOR T CELLS | ORUM THERAPEUTICS, INC. (KR) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023170608-A1 | ACTIVATORS OF EFFECTOR T CELLS | ORUM THERAPEUTICS, INC. (KR) | 2023-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304563-A1 | ACTIVATORS OF EFFECTOR T CELLS | CBLB, CBL, CBLC | PTGS1 4831/4885PTGS2 4736/4885FAAH 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.