Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264402 | 0.77 | EGFR (0.47) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL18264145 | 0.73 | CHEK1 (0.49) | APPMAP4K4CSF1RFGFR1PDGFRA | |
| SCHEMBL18264175 | 0.72 | KDM1A (0.52) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL21840862 | 0.69 | SLC2A1 (0.55) | KDRKDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL18264168 | 0.69 | MEN1 (0.52) | SMN1; SMN2MAPTKMT2AMEN1HTT | |
| SCHEMBL18264156 | 0.69 | NPY5R (0.50) | APPKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18264161 | 0.69 | ABCG2 (0.51) | APPKDRCLK4KDM4ENPC1 | |
| SCHEMBL18264174 | 0.69 | GAA (0.52) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL18264159 | 0.69 | MAPT (0.52) | APPKDRKDM4ENPC1RAB9A | |
| SCHEMBL18264403 | 0.67 | BTK (0.57) | MAP4K4PDGFRALTKKDRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-B1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | UNIV CHANG GUNG SCIENCE & TECHNOLOGY (TW) | 2023-09-13 | — | — | EP | disclosed |
| CN-113038949-B | Neutrophil inflammation inhibitor and application thereof | 长庚学校长庚科技大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-113038949-A | Neutrophilic leukocyte inflammation inhibitor and use thereof | 长庚学校财团法人长庚科技大学 | 2021-06-25 | — | — | CN | disclosed |