Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.51 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25415207 | 0.88 | BCL2 (0.59) | BCL2BECN1CACNA1HCACNA1CMEN1 | |
| SCHEMBL25416384 | 0.84 | BCL2 (0.68) | BCL2BECN1CACNA1HMEN1KMT2A | |
| SCHEMBL30369959 | 0.83 | BCL2 (0.77) | BCL2BECN1 | |
| SCHEMBL25560626 | 0.83 | BCL2 (0.77) | BCL2BECN1 | |
| SCHEMBL30370427 | 0.83 | BCL2 (0.62) | BCL2BECN1CACNA1HCACNA1C | |
| SCHEMBL25560154 | 0.83 | BCL2 (0.62) | BCL2BECN1CACNA1HCACNA1C | |
| SCHEMBL14540890 | 0.75 | BCL2 (0.68) | BCL2BECN1CACNA1HPKM | |
| SCHEMBL25414897 | 0.72 | BCL2 (0.77) | BCL2BECN1CACNA1H | |
| SCHEMBL30370125 | 0.68 | BCL2 (0.79) | BCL2BECN1 | |
| SCHEMBL23269270 | 0.68 | BCL2 (1.00) | BCL2BECN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081312-A1 | SMALL MOLECULE INDUCERS OF AUTOPHAGY | Vir Biotechnology, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081312-A1 | SMALL MOLECULE INDUCERS OF AUTOPHAGY | Vir Biotechnology, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |