SCHEMBL25415469

SCHEMBL25415469

CCC[Si](CCC)(CCC)CC(=Nc1c(C)cccc1C)c1cccc(C(C[Si](CCC)(CCC)CCC)=Nc2c(C)cccc2C)n1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.30
HSP90AA1 P07900 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30582652 0.92 CYP1A2 (0.33) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25416086 0.89 KCNH2 (0.36) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25411579 0.80 EPHX1 (0.31) CYP1A2
SCHEMBL30582649 0.80 KCNH2 (0.36) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25411988 0.80 KCNH2 (0.36) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL31286203 0.79 HPGD (0.30) HPGD
SCHEMBL25416432 0.79 HPGD (0.30) HPGD
SCHEMBL25936119 0.79 KDM4E (0.39) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25334797 0.79 KDM4E (0.39) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25331690 0.78 KDM4E (0.38) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179106-A1 Metal Bis(Imino) Aryl Compounds and Methods Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-06-05 US disclosed
EP-4493567-A1 METAL BIS(IMINO) ARYL COMPOUNDS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2025-01-22 EP disclosed
CN-118922428-A Metal bis (imino) aryl compounds and methods thereof 埃克森美孚化学专利公司 2024-11-08 CN disclosed
WO-2023177956-A1 METAL BIS(IMINO) ARYL COMPOUNDS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179106-A1 Metal Bis(Imino) Aryl Compounds and Methods Thereof SSB, BCL2L10, HNRNPA0 CYP1A2 3358/4885GRIN2D 3374/4885GRIN3B 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.