Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535471 | 1.00 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL2537368 | 1.00 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL2535472 | 1.00 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL2537364 | 1.00 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL2535468 | 1.00 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL3374518 | 0.93 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL3374520 | 0.93 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL2536052 | 0.86 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL3377897 | 0.86 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL2536055 | 0.86 | KCNH2 (0.51) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044044-B2 | 4-(1-amino-ethyl)-cyclohexylamine derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-10-25 | — | — | US | disclosed |