Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.54 |
| ▸ | BRDT | Q58F21 | 9/20 | 0.41 |
| ▸ | DNER | Q8NFT8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542006 | 1.00 | BRD4 (0.54) | BRD4BRDTDNER | |
| SCHEMBL2545008 | 0.92 | BRD4 (0.56) | BRD4BRDTDNER | |
| SCHEMBL2543538 | 0.92 | BRD4 (0.51) | BRD4BRDTDNER | |
| SCHEMBL2541102 | 0.87 | BRD4 (0.72) | BRD4BRDT | |
| SCHEMBL2541097 | 0.87 | BRD4 (0.72) | BRD4BRDT | |
| SCHEMBL3200582 | 0.86 | BRD4 (0.65) | BRD4BRDTDNER | |
| SCHEMBL2538956 | 0.84 | BRD4 (0.60) | BRD4BRDT | |
| SCHEMBL2538951 | 0.84 | BRD4 (0.60) | BRD4BRDT | |
| SCHEMBL2541824 | 0.84 | BRD4 (0.54) | BRD4BRDT | |
| SCHEMBL2541095 | 0.83 | BRD4 (0.57) | BRD4BRDTDNER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044042-B2 | Thienotriazolodiazepine compound and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |