Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAD | Q92934 | 2/20 | 0.88 |
| ▸ | BCL2 | P10415 | 11/20 | 0.79 |
| ▸ | BCL2L1 | Q07817 | 18/20 | 0.74 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.74 |
| ▸ | MDM4 | O15151 | 1/20 | 0.74 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | BID | P55957 | 1/20 | 0.74 |
| ▸ | BAX | Q07812 | 1/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.74 |
| ▸ | ASPH | Q12797 | 1/20 | 0.74 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.74 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.74 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.74 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422283 | 1.00 | BAD (0.88) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL1541222 | 0.94 | BAD (1.00) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL1540844 | 0.90 | BCL2 (0.87) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL2023941 | 0.90 | BCL2 (0.87) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL1541327 | 0.90 | BCL2 (0.86) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL1541323 | 0.90 | BCL2 (0.86) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL1541555 | 0.90 | BCL2 (0.86) | BADBCL2BCL2L1BCL2L2MDM4 | |
| Hydrochloric Acid SCHEMBL25421407 | 0.89 | BAD (0.83) | BADBCL2BCL2L1BCL2L2MDM4 | |
| Hydrochloric Acid SCHEMBL25421393 | 0.89 | BAD (0.83) | BADBCL2BCL2L1BCL2L2MDM4 | |
| SCHEMBL2019324 | 0.89 | BCL2 (1.00) | BADBCL2BCL2L1BCL2L2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107606-A1 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-15 | — | — | WO | disclosed |